Sodium Stearyl Fumarate
SMARTAB® is a tablet lubricant designed for formulations in which other lubricants lead to formulation and/or manufacturing challenges. As opposed to the frequently used lubricant, magnesium stearate, SMARTAB® offers the following advantages:
- Better API compatibility
- Robustness to over-lubrication
- No adverse effect on bioavailability
- Improved appearance of effervescent solutions.
SMARTAB® helps to accelerate product development and is particularly well suited for high-speed directly compressible granules and tablets.
Lot of Reported APIs having incompatibilities with magnesium stearate includes but not limited to : Azathioprin, Cefaclor, Cilazapril, Clopidogrel acetate, Dicofenac, Fosinopril, Ibuprofen, Ketorolac, Levofloxacin, Nifedipine, Omeprazole, Ramipril, Trandolapril and more…..
SMARTAB Benefits:
- Improved drug stability
- Faster dissolution rates
- Harder tablets
- Protection from over-blending
- Faster formulation development and scale-up
- Enhanced lubrication efficiency